Difference between revisions of "OLego"
From Zhang Laboratory
| Line 5: | Line 5: | ||
<center> | <center> | ||
| − | + | [[OLego_Documentation_v1.0.8|documentation]] |[[OLego_Documentation_v1.0.8#Download|download]] | |
</center> | </center> | ||
Revision as of 09:38, 21 November 2012
OLego is a program specifically designed for de novo spliced mapping of mRNA-seq reads. OLego adopts a multiple-seed-and-extend scheme, and does not rely on a separate external mapper. It achieves high sensitivity of junction detection by using very small seeds (12-14 nt), efficiently mapped using Burrows-Wheeler transform (BWT) and FM-index. This also makes it particularly sensitive for discovering small exons. It is implemented in C++ with full support of multiple threading, to allow fast processing of large-scale data.