Members

From Zhang Laboratory

Revision as of 17:44, 19 December 2022 by Czhang (Talk | contribs)

Jump to: navigation, search

Czlab 2022.jpeg

2022 Lab summer BBQ (10 year lab anniversary & celebration of Melissa's new faculty position)


PI

Chaolin2022.jpg

Chaolin Zhang

Associate Professor
Email: cz2294 (at) columbia (dot) edu

Curriculum Vitae

Personal page (old!)

Chaolin is currently an Associate Professor with joint appointments in Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, and Motor Neuron Center at Columbia University. Before he joined Columbia, he performed PhD studies at Cold Spring Harbor Laboratory in computational biology and then Postdoc work at Rockefeller University. Before that he obtained bachelor's degree studying Automation at Tsinghua University (Beijing). As a converted biologist originally trained in engineering, he has a deep interest in understanding gene regulatory logics. From the beginning of his academic endeavor, he decided to tackle the RNA code, i.e., how specific protein-RNA interactions determine the gene output in health and disease conditions, which remains the focus of the lab. Chaolin is a winner of NIH Pathway to Independence (K99/R00, 2011) and Maximizing Investigators' Research Award (MIRA/R35, 2022).



Current Lab Members


Georgia2022.jpg

Georgia Dermentzaki (09/2021-present), Postdoc

Email: gn2267 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Neuroscience, University of Athens; Biomedical Research Foundation of the Academy of Athens, Athens, Greece



Jassicae2022.jpg

Jessica Estrada (11/2022-present), Technician

Email: je2673 (at) cumc (dot) columbia (dot) edu

  • BA, Chemistry, Stony Brook University


Brian2022v2.jpg

Brian Joseph (11/2021-present), Postdoc (joint with Hynek Witchterle lab)

Email: bj2468 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Gerstner Sloan Kettering Graduate School of Biomedical Sciences


Brian joined the Zhang and Wichterle labs as a postdoctoral fellow in November 2021 after a brief research experience in Kevin Eggan’s motor neuron lab at Harvard. He completed his PhD with Eric Lai at the Sloan Kettering Institute in NYC focusing on the biology of cotranscriptional RNA processing mechanisms. He plans to explore RNA metabolism in neurons and hopes to identify novel vulnerabilities that can be the basis for therapeutic intervention. Brian is currently an ALS scholar in therapeutics.

A native Pakistani, Brian is obsessed with cricket and biryani. He is also an avid runner who still believes the PRs are yet to come.


Suvrajit2022.jpg

Suvrajit Maji (07/2022-present), Postdoc

Email:sm4073 (at) cumc (dot) columbia (dot) edu

  • Ph.D.,Carnegie Mellon University


Suvrajit is received his Bachelor's and Master's degree in Mathematics and Computing from the Indian Institute of Technology, Kharagpur, India. He then received his Ph.D. degree in computational biology from Carnegie Mellon University under the mentorship of his thesis advisor Dr. Marcel P. Bruchez. His thesis topic was single-molecule localization microscopy and super-resolution reconstruction of biological structures using generative models. He moved to Columbia University to continue his postdoctoral research work under the mentorship of Dr. Joachim Frank, when he focused on developing advanced mathematical, computer vision, and machine learning techniques for studying the structure and dynamics of molecular machines such as the Ribosomes and determining high-resolution 3D structures from 2D cryo-EM image datasets. His current research focuses on computational methods development, application, and analysis to study RNA-protein binding interactions using CLIP sequencing datasets. He is also involved in developing and applying machine learning & deep learning methods to study RNA-protein complex structures.

Personal page

Dan2022.jpg

Daniel Moakley (06/2018-), Graduate Student

Email: dfm2129 (at) cumc (dot) columbia (dot) edu

  • Ph.D. student, Integrative Program, Columbia University


Before coming to Columbia, Dan earned Bachelor’s and Master’s degrees from Wesleyan University, where he studied the maturation of ESC-derived interneurons in Laura Grabel’s laboratory. Then, he worked with Brian Wainger at Massachusetts General Hospital, where he focused on the electrophysiology of ESC-derived motor neurons. Dan is interested in molecular underpinnings of the immense cell type diversity in the brain. His work leverages both computational and experimental techniques to examine neuron type-specific alternative RNA splicing regulation. He uses the reanalysis of large, publicly available data sets to identify potential regulators of splicing differences across neuron types. These hypotheses are then tested in embryonic stem cell (ESC)-derived neurons.


Paola2022.jpg

Paola Rinchetti (05/2022-), Postdoc (joint with Francesco Lotti lab)

Email: pr2485 (at) cumc (dot) columbia (dot) edu

  • Ph.D., University of Milan



Yocelyn2022.jpg

Yocelyn Recinos (06/2018-), Graduate Student

Email: yr2330 (at) cumc (dot) columbia (dot) edu

  • Ph.D. student, Integrative Program, Columbia University
  • NSF GRFP awardee (2019)

Yocelyn received her B.S. in biological sciences from the University of California, Irvine and is a Ph.D. candidate in the Integrated Cellular, Molecular, and Biomedical program at Columbia University. For her thesis research, she is focused on developing high-throughput screening technologies to understand the role of RNA regulation in the context of alternative splicing and disease. Her work is supported by the NSF GRFP (2019). She also enjoys running in Central Park and practicing hot yoga.


Xiaojian2022.jpg

Xiaojian Wang (06/2016-), Lab manager

Email: xw2006 (at) columbia (dot) edu

  • MS, Molecular, Cellular and Developmental biology, the Ohio State University
  • BM, Basic Medical Sciences, Beijing Medical University, Beijing, China


Yuchen2022.jpg

Yuchen Xu (02/2022-), Master Student


Email: yx2709 (at) cumc (dot) columbia (dot) edu

  • Public Health in Biostatistics, Columbia University

Yuchen received his B.E degree in bioengineering from Northeastern University (China) in 2018. During his undergraduate study, he was previously involved in research work to study the relationship between TDP-43 protein and Lactoferrin treatment for the Alzheimer’s Disease. He is now a master student biostatistics at Columbia Mailman School of Public Health. In the Zhang lab, Yuchen studies spatial regulation of alternative splicing in the brain. In leisure times, Yuchen likes hiking or visiting coffee shops in NYC.

TimYeh2022.jpg

Tim Yeh (09/2022-), Postdoc


Email: yy2722 (at) cumc (dot) columbia (dot) edu

  • PhD, Department of Biology, Zukerman Mind Brain Behavior Institute, Columbia University


Alumni

Melissa Campbell (09/2019-11/2022), Postdoc

Email: mmc2259 (at) cumc (dot) columbia (dot) edu

  • M.D./Ph.D., Department of Genetics, NYU
  • NIH K99 awardee (2021)

Now: Assistant Professor, UCSD

Meghna Gopalan (06/2022-08/2022), Undergrad Summer Research Assistant

Email: mg4166 (at) barnard (dot) edu

  • Barnard College

Lydia Wu (10/2021-06/2022), Undergrad Research Assistant


Email: lw2892 (at) columbia (dot) edu

  • Columbia College



Huijuan Feng (8/2016-12/2021), Postdoc

Email: hf2304 (at) columbia (dot) edu

  • Ph.D., MOE Key Laboratory of Bioinformatics, Bioinformatics Division, TNLIST & Department of Automation, Tsinghua University
  • Visiting Ph.D. student (1/2015-1/2016)

Now: Associate Professor, Fudan University


Personal page


Suying Bao (06/2017-06/2021), Postdoc

Email: sb4045 (at) columbia (dot) edu

  • Ph.D., School of Biomedical Sciences, The University of Hong Kong

Now: Bioinformatics Manager, Regeneron


Dmytro Ustianenko (01/2015-05/2021), Postdoc

Email: du2145 (at) columbia (dot) edu

  • Ph.D., Biomolecular Chemistry, Masaryk University, Central European Institute of Technology, Brno, Czech Republic

When existing: Blavatnik Fellow in Life Science Entrepreneurship, Yale University

Now: Associate, Flagship Pioneering

Lily Wang (07/2020-09/2020), Undergraduate Research Assistant

Undergraduate student, Mathematics/Statistics, Columbia University
Email: hw2744 (at) columbia (dot) edu

  • Amgen Summer Research Program Award (2020)



Lekha Yesantharao (09/2017-12/2019), Undergraduate Research Assistant Undergraduate student, Department of Engineering, Columbia University
Email: lvy2002 (at) columbia (dot) edu

  • Simons Foundation Undergraduate Summer Research Program Award (2018)

Now: Medical School, Johns Hopkins School of Medicine

Justin Wong (06/2017-05/2019), Undergraduate Research Assistant Undergraduate student, Department of Computer Science, Columbia University
Email: justin (dot) wong (at) columbia (dot) edu

  • Simons Foundation Undergraduate Summer Research Program Award (2017)

Now: Graduate Student, UC Berkeley

Brittany Phillips (05/2018-05/2019), Postdoc

Email: bp2563 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Genetics and Molecular Biology, Emory University

Now: Medical Writer, Chrysalis Medical Communications

Yingzhi Qian (06/2016-06/2018), Computational Biologist

Email: yq2139 (at) columbia (dot) edu

  • M.A., Statistics, Columbia University
  • B.Sc., Applied Mathematics, Fudan University

Now: Research Scientist, NYU Lagone Health


Sebastien Weyn (08/2013-02/2018), Graduate Student

Ph.D. student, Integrative Program, Columbia University
Email: smw2185 (at) columbia (dot) edu

  • Titus M Coan Award for Excellence in Research (2018)


Now: Bioinformatics Scientist, Stoke Therapeutics.

Helene Lovett (06/2017-08/2017), Undergraduate Research Assistant

Undergraduate student, Department of Neurobiology, Harvard University
Email: helenelovett (at) college (dot) Harvard (dot) edu

  • SURF/Amgen Fellowship (2017)

Martin Jacko (08/2013-07/2017), Graduate Student

Ph.D. student (joint with Wichterle lab), Department of Pathobiology & Molecular Medicine, Columbia University
Email: mj2577 (at) columbia (dot) edu


When exiting: Postdoc, Alice Ting Lab, Stanford University

Now: Associate Director, Business Development & Operations at Bridgebio

Ankeeta Shah (08/2015-05/2017), Volunteer

Undergraduate student, Barnard College
Email: abs2218 (at) barnard (dot) edu

  • SURF/Amgen Fellowship (2016)
  • Goldwater Scholarship (2016)

Now: Graduate Student, University of Chicago

Jonah Lee (05/2015-01/2017), Volunteer

Undergraduate student, Columbia College
Email: jl3910 (at) columbia (dot) edu


Andrew Arditi (Volunteer, 09/2016-12/2016)
Columbia College
Email: ava2123 (at) columbia (dot) edu

Jingxian You (Volunteer, 07/2016-09/2016)
Fudan University
Email: ykevingrox (at) gmail (dot) com

Jiaye Li (05/2016-08/2016)

MA in Biotechnology, Columbia University

Then: Volunteer

Kevin Huynh (10/2015-7/2016)

  • BS, Biochemistry/Cell Biology, UCSD
  • MS, Biology, UCSD

Then: Technician

Now: MD program, UCSF

Joy Pai ( 09/2013-05/2016)
Undergraduate student, Departments of Biological Sciences and Computer Science, Columbia University

  • Harvard/MIT HST Summer Institute Fellowship (2015)
  • SURF/Amgen Fellowship (2014)

Then: Undergraduate Research Assistant

When existing: Bioinformatics specialist, Michel Russenzweig lab, Rockefeller University

Now: Graduate Student, Stanford University

Kernyu Park (07/2015-10/2015)
Departments of Biological Sciences and Computer Science, Columbia University

Then: Undergraduate Research Assistant

Qinghong Yan (02/2013-02/2015)
Ph.D., Department of Neurobiology & Behavior, Stony Brook University
Then: Postdoc
When existing: Scientist, Amgen

Now: Head of Biology, FUSION BioVenture

Yong Zhang (04/2013-11/2014)
Ph.D., Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Then: Postdoc
Now: Postdoc, Xuemei Chen lab, UC Riverside

Jie Wu (01/2013-08/2013)

Then: Visiting Ph.D. student, Cold Spring Harbor Laboratory / Applied Maths and Statistics, Stony Brook University
When existing: Bioinformatics Scientist, BioMicro Center, MIT

Now: Associate Director, Bioinformatics at Accent Therapeutics, Inc.