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'''PI'''
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[[File:Lab photo 2024 v2s.jpg|920px|center|Zhang lab photo, 2024 @ Columbia University Irving Medical Center|link=https://zhanglab.c2b2.columbia.edu/index.php/Members]]
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Zhang lab photo, 2024 @ Columbia University Irving Medical Center
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==PI==
 
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<img src="/data/images/chaolin_small.jpg" width="128" height="158">
 
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|'''Chaolin Zhang''' <br/>
 
Assistant Professor <br/>
 
Email: cz2294 (at) columbia (dot) edu <br/>
 
  
*Research Ass. Prof., Rockefeller University (2011-2012)
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[[File:Chaolin2022.jpg|400px|link=]]
*Postdoc, Rockefeller University (2008-2011)
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*Ph.D., Cold Spring Harbor Laboratory / Stony Brook University (2004-2008)
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|'''Chaolin Zhang''' [[File:Twitter.jpg|25px|link=https://twitter.com/chaolinzhang]] [[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/chaolin-zhang-52835217/]] <br/>
*B.E., Tsinghua University, Beijing (1998-2002)
+
Associate Professor, Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, Motor Neuron Center <br/>
 +
Email: cz2294 (at) columbia (dot) edu <br/>
  
 
<html>
 
<html>
<a href="/data/zhangc_cv.pdf">Curriculum Vitae</a> |
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 +
<a href="https://zhanglab.c2b2.columbia.edu/images/a/a0/Zhangc.cv.20211103.pdf">Curriculum Vitae</a>
 
</html>
 
</html>
[[Chaolin Zhang|Personal page]]
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 +
[[Chaolin Zhang|Personal page (old!)]]
 +
 
 +
Chaolin is currently an Associate Professor with joint appointments in [http://systemsbiology.columbia.edu Department of Systems Biology], [http://www.biochem.cuimc.columbia.edu Department of Biochemistry and Molecular Biophysics], and [http://www.vagelos.columbia.edu/departments-centers/motor-neuron-center Motor Neuron Center] at [http://www.cuimc.columbia.edu Columbia University Irving Medical Center].  Before he joined Columbia, he performed PhD studies at [http://www.cshl.edu Cold Spring Harbor Laboratory] in computational biology and then Postdoc work on computational and molecular biology at [http://www.rockefeller.edu Rockefeller University].  Before that he obtained bachelor's degree studying Automation at [http://www.tsinghua.edu.cn Tsinghua University] (Beijing).  As an engineer-converted biologist, he has a deep interest in understanding gene regulatory logics.  From the beginning of his academic endeavor, he decided to tackle the RNA code, i.e., how specific protein-RNA interactions determine the gene output in health and disease conditions, which remains the focus of the lab. Chaolin is a winner of Pathway to Independence Award (K99/R00, 2011) and Maximizing Investigators' Research Award (MIRA/R35, 2022) from NIH, and Scientific Innovations Award from the Brain Research Foundation (2023).
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'''Staff Associate'''
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==Current Lab Members==
 
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[[File:Xiaojianprofilepic.jpeg|130px]]
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|'''Xiaojian Wang''' (06/2016-)<br/>
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Lab manager <br/>
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[[File:ChamariAbercrombie.jpg|400px|link=]]
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|  
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/chamari-abercrombie-532a7a199/]]
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 +
'''Chamari Abercrombie''' (07/2024-), '''Postbac'''
 +
 
 +
Email: ca3176 (at) columbia (dot) edu
 +
 
 +
*BA, Neuroscience-Biology, College of Wooster<br/>
 +
 
 +
Chamari received her BA in Neuroscience-Biology from The College of Wooster in Ohio. During her last year of undergrad, she completed her
 +
Independent Study by analyzing epilepsy in Drosophila melanogaster. Chamari’s goal is to pursue an MD/PhD as a neurosurgeon to contribute to research that aligns with her goals of providing adequate patient care and development of effective but safe medication. Originally from Atlanta, Georgia, Chamari is excited to explore the city. In her free time, she loves to work out and try new restaurants.
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|-
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|style="width: 1px"|
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[[File:Shahalam.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/shah-bonn/]]
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'''Shah Alam''' (06/2023-), '''Postdoc'''
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 +
Email: sa4354 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D., Molecular Medicine, University of Bonn, Germany<br/>
 +
 
 +
Shah joined Zhang's lab in June 2023 as a postdoctoral research scientist. Prior to joining
 +
Columbia, he gained experience working as a postdoc at the LIMES Institute, University of
 +
Bonn, Germany, for over a year. He also completed his PhD at the same institute. During his
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PhD, he unraveled the signaling of sphingosine-1-phosphate (S1P) in primary neurons, microglia,
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and astrocytes of a neurodegenerative disease mouse model called neural-cell specific S1P-lyase
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(SGPL1) deficient mice. He earned his master's degree in molecular biotechnology from the
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University of Bonn and his bachelor's degree in biotechnology from VIT University, India. Shah's
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current research plans involve delving into the regulatory mechanisms and lineage-specific alternatively splicing events and their functional impacts on brain development and developmental disorders. Moreover, he is also interested in developing
 +
experimental systems that will strategically map and compare RBP binding sites and RBP-dependent
 +
splicing regulation in neurons. Beyond his academic pursuits, he is particularly passionate about cricket,
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running, and hiking.
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|-
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|style="width: 1px"|
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[[File:Shane chu.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/kchu1/]]
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'''Shane Chu''' (01/2024-), '''Postdoc'''
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 +
Email: sc5502 (at) cumc (dot) columbia (dot) edu
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 +
*Ph.D., Department of Computer Science, Washington University at Saint Louis<br/>
 +
 
 +
[http://kchu25.github.io Personal page]
 +
 
 +
Shane Chu earned his PhD in computer science from Washington University in St. Louis, working with Gary Stormo.  His PhD work focused on developing interpretable representation learning methods for addressing challenges in protein-DNA/RNA interactions. Outside of his academic pursuits, he finds relaxation and enjoyment in playing tennis and visiting the Peridance Center in NYC.
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|-
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|style="width: 1px"|
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[[File:Wangyang.jpg|400px|link=]]
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|
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'''Wangyang Dai''' (10/2023-), '''Master Student'''
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 +
Email: wd2383 (at) columbia (dot) edu
 +
 
 +
*Master student, Biotechnology, Columbia University
 +
*BS, Fudan University, Shanghai, China (2023)
 +
 
 +
Wangyang obtained her Bachelor's degree in Life Sciences from Fudan University in 2023. During her time as an undergraduate student, she conducted research on proline metabolism and its effects on ATF4 regulation. Later, she developed an interest in the RNA world (cool!), specifically focusing on alternative splicing and its correlation with neuron cell properties within and across cell types. Now in the Zhang lab, she is involved in a project about analysis of CLIP data using crosslink-induced mutation sites (CIMS) and aims to utilize it as a signature to better understand RBP binding specificity. Besides academics, she enjoys exploring good food, visiting museums, and building her own coffee map here in New York.
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|-
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|style="width: 1px"|
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[[File:Jassicae2022.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/jessicaestrada928/]]
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'''Jessica Estrada''' (11/2022-), '''Technician'''
 +
 
 +
Email: je2673 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*BA, Chemistry, Stony Brook University <br/>
 +
 
 +
Jessica received her B.A from Stony Brook University in Chemistry and is a Technician in the Zhang Lab. She assists on various projects in the lab while developing a research focus, and plans on pursing a PhD in the biomedical sciences. In her free time, she likes to go on hikes and cook for friends and family.
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|-
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|style="width: 1px"|
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[[File:Brian2022v2.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/brian-joseph-37b012152/]]
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'''Brian Joseph''' (11/2021-), '''Postdoc''' (joint with Hynek Witchterle lab)
 +
 
 +
Email: bj2468 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D., Gerstner Sloan Kettering Graduate School of Biomedical Sciences <br/>
 +
*New York Stem Cell Foundation Research Institute (NYSCF) Druckenmiller Fellows (2023)
 +
 
 +
Brian joined the Zhang and Wichterle labs as a postdoctoral fellow in November 2021 after a brief research experience in Kevin Eggan’s motor neuron lab at Harvard. He completed his PhD with Eric Lai at the Sloan Kettering Institute in NYC focusing on the biology of cotranscriptional RNA processing mechanisms.  He plans to explore RNA metabolism in neurons and hopes to identify novel vulnerabilities that can be the basis for therapeutic intervention. Brian is currently an ALS scholar in therapeutics.
 +
 +
A native Pakistani, Brian is obsessed with cricket and biryani. He is also an avid runner who still believes the PRs are yet to come.
 +
 
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|-
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|style="width: 1px"|
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[[File:Dan2022.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/daniel-moakley-b0b66342/]]
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'''Daniel Moakley''' (06/2018-), '''Graduate Student'''
 +
 
 +
Email: dfm2129 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D. student, Integrative Program, Columbia University<br/>
 +
 
 +
 
 +
Before coming to Columbia, Dan earned Bachelor’s and Master’s degrees from Wesleyan University, where he studied the maturation of ESC-derived interneurons in Laura Grabel’s laboratory. Then, he worked with Brian Wainger at Massachusetts General Hospital, where he focused on the electrophysiology of ESC-derived motor neurons. Dan is interested in molecular underpinnings of the immense cell type diversity in the brain. His work leverages both computational and experimental techniques to examine neuron type-specific alternative RNA splicing regulation. He uses the reanalysis of large, publicly available data sets to identify potential regulators of splicing differences across neuron types. These hypotheses are then tested in embryonic stem cell (ESC)-derived neurons.
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|-
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|style="width: 1px"|
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[[File:Paola2022.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/paola-rinchetti-449931107/]]
 +
 
 +
'''Paola Rinchetti''' (05/2022-), '''Postdoc'''
 +
 
 +
Email: pr2485 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D., University of Milan
 +
 
 +
Paola's research career started in 2014 in Prof. Stefania Corti's lab at University of Milan. During her studies in Italy, she maximized her knowledge in the field of cellular biology and in particular in the use of induced pluripotent stem cells (iPSCs) and 2D models to study neurodegenerative diseases such as SMA and ALS and the development of potential treatments. During her PhD, she mainly focused on the generation of new 3D models to investigate the pathological mechanism underlying SMA and ALS. During this time, she was also involved in exchange programs with the laboratory of Prof. Prezdborsky and Prof. Lotti at Columbia University where she was able to deepen her knowledge in the field of in vivo models.  In the Zhang lab, she is working on RNA-based medicine for neurodevelopmental disorders.
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|-
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|style="width: 1px"|
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[[File:Lea_radomsky.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/lea-radomsky/]]
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 +
'''Lea Radomsky''' (09/2024-), '''Technician'''
 +
 
 +
Email: lr3280 (at) columbia (dot) edu <br/>
 +
 
 +
*Certified Professional Training as Biology Lab Technician, Technical University of Munich, Germany
 +
 
 +
Lea completed her vocational training in Germany at the Technical University of Munich from 2018 to 2021. Between 2018 and 2024, she worked with Prof. Angelika Schnieke and Prof. Benjamin Schusser, focusing on advanced molecular and cell culture techniques. In September 2024, she joined the Zhang lab, where she supports postdoctoral researchers with molecular experiments and cell culture work. Outside the lab, Lea enjoys Pilates and exploring New York City.
 +
 
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|-
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|style="width: 1px"|
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[[File:Ruchika.JPG|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/dr-ruchika-p-hd-b5574219a/]]
 +
 
 +
'''Ruchika''' (07/2023-), '''Postdoc'''
 +
 
 +
Email: fr2563 (at) columbia (dot) edu <br/>
 +
 
 +
*PhD, School of Material Science, Japan Advanced Institute of Science and Technology, Japan
 +
 
 +
Ruchika completed her doctoral degree in molecular biology from Japan Advanced Institute of Science and Technology (JAIST) in Japan in 2022. During PhD, she worked on the identification and characterization of U-to-C RNA editing events in plants and used a plant-derived pentatricopeptide repeat (PPR) proteins to develop an artificial deamination system for C-to-U RNA editing in mammalian cells, and received an Excellent student award for her work. Thereafter, she joined Kyushu University in Fukuoka, Japan, as an assistant professor and she worked on designer PPR proteins to target long non-coding RNAs, especially related to neurodegenerative diseases and cancer. At the next step, Ruchika is excited for multiple projects related to programmable RNA targeting using different approaches at Columbia.
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|-
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|style="width: 1px"|
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[[File:Cynthiawang.png|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/cynthia-wang-69423b1aa/]]
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 +
'''Tianxin (Cynthia) Wang''' (09/2024-), '''Graduate Student (in Rotation)'''
 +
 
 +
Email: tw3056 (at) columbia (dot) edu <br/>
 +
 
 +
*B.S., Biological Sciences, University of Chicago
 +
 
 +
Cynthia is a first-year PhD student in the Systems Biology Department. Before coming to Columbia, she earned her Bachelor’s from the University of Chicago. During her studies, she conducted both experimental and computational research and developed a passion for the RNA world. In Prof. Tao Pan’s lab, she facilitated the development and optimization of an engineered missense-correcting tRNA as potential therapeutics for correcting pathogenic mutations. In Prof. Matthias Steinruecken's lab, she statistically evaluated how including the genetically linked locus affected the time-series inference of natural selection at its surrounding loci. Now, she has joined the Zhang lab as a rotation student, where she is excited to work on designing tools to target neurodegenerative disease-related RNAs. Outside of lab, she enjoys doing yoga, working out, exploring good food, and traveling to experience diverse cultures.
 +
 
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|-
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|style="width: 1px"|
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[[File:Xiaojian2022.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/xiaojian-wang-087a153a/]]
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 +
'''Xiaojian Wang''' (06/2016-), '''Lab manager'''
 +
 
 
Email: xw2006 (at) columbia (dot) edu <br/>
 
Email: xw2006 (at) columbia (dot) edu <br/>
  
 
*MS, Molecular, Cellular and Developmental biology, the Ohio State University
 
*MS, Molecular, Cellular and Developmental biology, the Ohio State University
 
*BM, Basic Medical Sciences, Beijing Medical University, Beijing, China
 
*BM, Basic Medical Sciences, Beijing Medical University, Beijing, China
 +
 +
Before coming to work at Columbia, Xiaojian earned her Bachelor’s and Master’s degrees from Beijing Medical University and the Ohio State University, respectively. At CUIMC, she worked as supporting staff and lab manager in several labs.  She joined the Zhang lab in 2016, and has been providing support on both molecular biology experiments and mouse work, as well as daily lab operations.  In her free time, Xiaojian enjoys cooking, watching baseball games, and spending time with her family.
 +
 +
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
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[[File:YeWang.jpg|400px|link=]]
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|
  
[[File:YQianprofilepic.jpeg|130px]]
 
  
|'''Yingzhi Qian''' (06/2016-)<br/>
+
'''Ye Wang''' (02/2024-), '''Postdoc'''
Computational Biologist <br/>
+
Email: yq2139 (at) columbia (dot) edu <br/>
+
  
*M.A., Statistics, Columbia University
+
Email: yw4291 (at) columbia (dot) edu <br/>
*B.Sc., Applied Mathematics, Fudan University
+
|}
+
  
 +
*PhD, Tsinghua National Laboratory for Information Science and Technology, Department of Automation, Tsinghua University, Beijing, China.
  
 +
Prior to joining Zhang lab, Ye obtained her PhD training on computational and synthetic biology in Tsinghua university. During her PhD, she proposed an AI-based generative framework for the de novo design of promoter elements in Escherichia coli, which showed a high success rate based on
 +
experimental validation in vivo.  For her postdoc research, she plans to focus on inverse design of synthetic exons/introns to understand splicing regulation and their function in brain and developmental disorders, with an ultimate goal to facilitate the development of RNA-based precision genetic medicine. Outside the lab, Ye is passionate about yoga, running, and cooking.
  
'''Postdocs'''
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|-
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|style="width: 1px"|
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[[File:TimYeh2022.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/yowtyngyeh/]]
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 +
'''Tim Yeh''' (09/2022-), '''Postdoc'''
 +
 
 +
 
 +
Email: yy2722 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*PhD, Department of Biology, Zukerman Mind Brain Behavior Institute, Columbia University
 +
 
 +
Tim  received  his  Ph.D.  in  Biological  Sciences  from  Columbia  University  (2022).
 +
Throughout his scientific career, he has been interested in understanding how the brain
 +
works and developing treatment. His graduate research focused on auditory processing
 +
in the brain and sensorimotor interaction. As a postdoc in the Zhang lab, Tim hopes to
 +
investigate the roles of RNA splicing in normal brain functions and neurological diseases
 +
using novel research methods such as gene editing tools and sequencing technologies.
 +
When he is not doing science, he likes to play tennis and ping pong. He is also a foodie
 +
who enjoys eating pizza!
 +
 
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|-
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|style="width: 1px"|
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[[File:Tianji2023s.jpg|400px|link=]]
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|
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[[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/tianji-yu-32604322b/]]
 +
 
 +
'''Tianji Yu''' (07/2024-), '''Graduate Student'''
 +
 
 +
 
 +
Email: ty2514 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*BA, Quantitative Biology, UNC Chapel Hill
 +
 
 +
Tianji is a first-year Ph.D. student in the Systems Biology Department. Before he came to Columbia, he earned a Bachelor's degree from UNC Chapel Hill. At UNC, his research focused on cell cycle regulation in endothelial cells and AU-rich elements RNA binding proteins. During his undergraduate research, he practiced both experimental and computational techniques. Now he is excited to conduct new research here at Columbia University. In Zhang's lab, he is working on RNA base editing for his rotation project. Besides research, he likes soccer and food. He is also fascinated with karting race.
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|-
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|style="width: 1px"|
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[[File:MatthewY2023s.jpg|400px|link=]]
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|
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'''Matthew Yuan''' (06/2023-), '''Visiting High School Student (remote)'''
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 +
Matthew currently attends Lynbrook High School in San Jose, California as a rising Sophomore, and is passionate about Math and Science. Matthew is a two-time AIME qualifier, and has years of experience in Science Olympiad and Science Bowl. His favorite research area is Marine Biology. In his spare time, Matthew enjoys reading and writing, playing basketball as well as playing video games (Geometry Dash and Crossy Road are his favorites).
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|}
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==Alumni==
  
 
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|-
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|style="width: 400px"|
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'''Name/Position in the Lab'''
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|
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'''Position When Exiting'''
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|
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'''Current Position'''
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|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
<html>
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<img src="/data/images/dima.jpg" width="128" height="162">
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/suvrajitmaji/]]
</html>
+
'''Suvrajit Maji''' (07/2022-06/2024), '''Postdoc'''
| '''Dmytro Ustianenko''' (01/2015-)<br/>
+
 
Postdoc<br/>
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Email:sm4073 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D.,Carnegie Mellon University <br/>
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[http://www.columbia.edu/~sm4073/ Personal page]
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|
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Senior Research Scientist, NYU Langone Health
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|
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|-
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|style="width: 1px"|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/yocelyn-recinos-phd-8992b2172//]]
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'''Yocelyn Recinos''' (06/2018-01/2024), '''Graduate Student'''
 +
 
 +
Email: yr2330 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D. student, Integrative Program, Columbia University
 +
*NSF GRFP awardee (2019)
 +
*Dean's Award for Excellence in Research (2024)
 +
 
 +
|  Scientific Analyst, Morrison Foerster
 +
 
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|
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|-
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|style="width: 1px"|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/georgia-dermentzaki/]]
 +
'''Georgia Dermentzaki''' (09/2021-11/2023), '''Postdoc'''
 +
 
 +
Email: gn2267 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Ph.D., Neuroscience, University of Athens; Biomedical Research Foundation of the Academy of Athens, Athens, Greece<br/>
 +
 
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|
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Senior Scientist, Sanofi
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|
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|-
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|style="width: 400px"|
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[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/mckenziecampbellmdphd/]]
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'''Melissa Campbell''' (09/2019-11/2022), '''Postdoc'''
 +
 
 +
Email: mmc2259 (at) cumc (dot) columbia (dot) edu <br/>
 +
 
 +
*M.D./Ph.D., Department of Genetics, NYU
 +
*NIH K99 awardee (2021)
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|
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Assistant Professor, UCSD
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|
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|-
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|style="width: 1px"|
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 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/huijuan-feng-72773733/]]
 +
'''Huijuan Feng''' (8/2016-12/2021), '''Postdoc'''
 +
 
 +
Email: hf2304 (at) columbia (dot) edu
 +
*Ph.D., MOE Key Laboratory of Bioinformatics, Bioinformatics Division, TNLIST & Department of Automation, Tsinghua University<br/>
 +
*Visiting Ph.D. student (1/2015-1/2016)
 +
 
 +
[http://huijfeng.github.io Personal page]
 +
 
 +
|
 +
Associate Professor, Fudan University
 +
 
 +
|
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/suying-bao-60217622/]]
 +
'''Suying Bao''' (06/2017-06/2021), '''Postdoc'''
 +
 
 +
Email: sb4045 (at) columbia (dot) edu <br/>
 +
 
 +
*Ph.D., School of Biomedical Sciences, The University of Hong Kong
 +
 
 +
|
 +
Bioinformatics Manager, Regeneron
 +
|
 +
 
 +
Seinior Manager Computational Genomics, Regeneron
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/dmytro-ustianenko/]]
 +
'''Dmytro Ustianenko''' (01/2015-05/2021), '''Postdoc'''
 +
 
 
Email: du2145 (at) columbia (dot) edu
 
Email: du2145 (at) columbia (dot) edu
  
 
*Ph.D., Biomolecular Chemistry, Masaryk University, Central European Institute of Technology, Brno, Czech Republic <br/>
 
*Ph.D., Biomolecular Chemistry, Masaryk University, Central European Institute of Technology, Brno, Czech Republic <br/>
 +
 +
|
 +
Blavatnik Fellow in Life Science Entrepreneurship, Yale University
 +
 +
|
 +
Associate, Flagship Pioneering
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
<html>
+
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/phillipsbl/]]
<img src="/data/images/huijuan.jpg" width="128" height="158">
+
'''Brittany Phillips''' (05/2018-05/2019), '''Postdoc'''
</html>
+
| '''Huijuan Feng''' (08/2016-)<br/>
+
Postdoc<br/>
+
Email: hf2304 (at) columbia (dot) edu
+
  
*Visiting Ph.D. student (1/2015-1/2016)
+
Email: bp2563 (at) cumc (dot) columbia (dot) edu
*Ph.D., MOE Key Laboratory of Bioinformatics, Bioinformatics Division, TNLIST & Department of Automation, Tsinghua University<br/>
+
  
 +
*Ph.D., Genetics and Molecular Biology, Emory University<br/>
  
|}
+
|
 +
Medical Writer, Chrysalis Medical Communications
  
 +
|
  
 +
Medical Writing Senior Manager, Amgen
  
'''Graduate students'''
+
|-
 +
|style="width: 1px"|
  
{|class="zebra wikitable" width="100%" style="border:1px solid; border-collapse:collapse;"
+
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/sebweyn/]]
 +
'''Sebastien Weyn''' (08/2013-02/2018), '''Graduate Student'''
  
 +
Ph.D. student, Integrative Program, Columbia University<br/>
 +
Email: smw2185 (at) columbia (dot) edu
  
 +
* Titus M Coan Award for Excellence in Research (2018)
 +
 +
|
 +
Bioinformatics Scientist, Stoke Therapeutics.
 +
 +
|
 +
 +
Principal Scientist, Bioinformatics, Fosun Pharma USA Inc.
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
<html>
+
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/martin-jacko-1a1989118/]]
<img src="/data/images/martin.jpg" width="128" height="154">
+
'''Martin Jacko''' (08/2013-07/2017), '''Graduate Student'''
</html>
+
| '''Martin Jacko''' (08/2013-)<br/>
+
  
 
Ph.D. student (joint with Wichterle lab), Department of Pathobiology & Molecular Medicine, Columbia University<br/>
 
Ph.D. student (joint with Wichterle lab), Department of Pathobiology & Molecular Medicine, Columbia University<br/>
 
Email: mj2577 (at) columbia (dot) edu
 
Email: mj2577 (at) columbia (dot) edu
  
 +
|
 +
Postdoc, Alice Ting Lab, Stanford University
 +
 +
|
 +
CEO, Aperture Therapeutics
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
<html>
+
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/qinghong-yan/]]
<img src="/images/c/cc/Seb3.jpg" width="128" height="149">
+
'''Qinghong Yan''' (02/2013-02/2015), '''Postdoc'''<br/>
</html>
+
Ph.D., Department of Neurobiology & Behavior, Stony Brook University <br/>
| '''Sebastien Weyn''' (08/2013-)<br/>
+
  
Ph.D. student, Columbia University<br/>
 
Email: smw2185 (at) columbia (dot) edu
 
  
 +
|
 +
Scientist, Amgen
  
 +
|
  
|}
+
CSO, Leverna Therapeutics
  
 +
|-
 +
|style="width: 1px"|
 +
'''Yong Zhang''' (04/2013-11/2014), '''Postdoc'''<br/>
 +
Ph.D., Institute of Genetics and Developmental Biology, Chinese Academy of Sciences<br/>
  
  
'''Undergraduate/volunteer'''
+
|
 +
Postdoc, Xuemei Chen lab, UC Riverside
  
{|class="zebra wikitable" width="100%" style="border:1px solid; border-collapse:collapse;"
+
|
  
 +
Research Scientist, USDA
  
 +
|-
 +
|style="width: 1px"|
 +
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/jie-wu-8592526/]]
 +
'''Jie Wu''' (01/2013-08/2013)<br/>
 +
 +
Visiting Ph.D. student, Cold Spring Harbor Laboratory / Applied Maths and Statistics, Stony Brook University <br/>
 +
|
 +
Bioinformatics Scientist, BioMicro Center, MIT
 +
|
 +
Associate Director, Bioinformatics at Accent Therapeutics, Inc.
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
<html>
+
 
<img src="/data/images/jonah.jpg" width="128" height="152">
+
 
</html>
+
|
| '''Jonah Lee''' (Volunteer, 05/2015-)<br/>
+
 
Columbia College<br/>
+
|
Email: jl3910 (at) columbia (dot) edu
+
 
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
 +
'''Qiyang Wu''' (01/2013-), '''Master Student'''
  
<html>
+
Email:qw2388 (at) columbia (dot) edu <br/>
<img src="/data/images/Ankeeta.jpg" width="128" height="152">
+
</html>
+
| '''Ankeeta Shah''' (Volunteer, 08/2015-)<br/>
+
Barnard College<br/>
+
Email: abs2218 (at) barnard (dot) edu
+
  
* SURF/Amgen Fellowship (2016)
+
*Master of Science Program in Biomedical Engineering, Columbia University
* Goldwater Scholarship (2016)
+
*BE, The Chinese University of Hong Kong, Shenzhen, China (2022)
 +
 
 +
|
 +
 
 +
|
  
  
Line 152: Line 611:
 
|style="width: 1px"|
 
|style="width: 1px"|
  
[[File:jingxian.jpeg|130px]]
 
| '''Jingxian You''' (Volunteer, 07/2016-)<br/>
 
Fudan University<br/>
 
Email: ykevingrox (at) gmail (dot) com
 
  
 +
[[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/fahad-paryani-7a042b153/]]
 +
'''Fahad Paryani''' (09/2023-), '''Rotation Student'''
  
|}
+
Email: fp2409 (at) cumc (dot) columbia (dot) edu
  
 +
*Ph.D. student, Integrated Program, Columbia University<br/>
  
  
'''Alumni'''
+
|
  
{|class="zebra wikitable" width="100%" style="border:1px solid; border-collapse:collapse;"
+
|
  
 
|-
 
|-
 +
|style="width: 1px"|
  
 +
 +
[[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/albertinemcdowellneal/]]
 +
'''Albertine Neal''' (09/2023-), '''Rotation Student'''
 +
 +
Email: amn2201 (at) cumc (dot) columbia (dot) edu
 +
 +
*Ph.D. student, Integrated Program, Columbia University <br/>
 +
 +
|
 +
 +
|
 +
 +
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
'''Jiaye Li''' (Volunteer, 05/2016-08/2016)<br/>
+
[[File:LinkedIn.png|20px|link=https://www.linkedin.com/in/tianji-yu-32604322b/]]
 +
'''Tianji Yu''' (09/2023-), '''Rotation Student'''
  
Then: MA in Biotechnology, Columbia University
+
 
 +
Email: ty2514 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*BA, Quantitative Biology, UNC Chapel Hill
 +
 
 +
|
 +
 
 +
|
  
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
 +
'''Madeline (Maddie) Scanlon''' (06/2023-09/2023), '''Visiting High School Student'''
  
  
'''Kevin Huynh''' (10/2015-7/2016)<br/>
+
*High school studnet, King School, Stamford, CT
Then: Technician
+
  
Now: MD program, UCSF
+
|
 +
 
 +
|
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
 +
'''Vivian Coraci''' (07/2023-09/2023), '''Visiting High School Student'''
  
'''Joy Pai''' (Volunteer, 09/2013-05/2016)<br/>
 
Then: Undergraduate student, Departments of Biological Sciences and Computer Science, Columbia University<br/>
 
* Harvard/MIT HST Summer Institute Fellowship (2015)
 
* SURF/Amgen Fellowship (2014)
 
  
Now: Bioinformatics specialist, Michel Russenzweig lab, Rockefeller University
+
*High school student, Horace Mann School in the Bronx.
 +
 
 +
|
 +
 
 +
|
 +
 
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
  
 +
'''Yuchen Xu''' (02/2022-05/2023), '''Master Student'''
  
'''Kernyu Park''' (Volunteer, 07/2015-10/2015)<br/>
+
 
Departments of Biological Sciences and Computer Science, Columbia University
+
Email: yx2709 (at) cumc (dot) columbia (dot) edu
 +
 
 +
*Public Health in Biostatistics, Columbia University
 +
 
 +
|
 +
 
 +
Research Technician, Abbas Rizvi Lab, University of Wisconsin-Medison
 +
 
 +
|
  
  
Line 205: Line 698:
 
|style="width: 1px"|
 
|style="width: 1px"|
  
'''Qinghong Yan''' (02/2013-02/2015)<br/>
+
'''Lily Wang''' (07/2020-09/2020), '''Undergraduate Research Assistant'''
Ph.D., Department of Neurobiology & Behavior, Stony Brook University <br/>
+
 
Then: Postdoc<br/>
+
Undergraduate student, Mathematics/Statistics, Columbia University<br/>
Now: Scientist, Amgen
+
Email: hw2744 (at) columbia (dot) edu <br/>
 +
 
 +
*Amgen Summer Research Program Award (2020)
 +
|
 +
 
 +
|
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
'''Yong Zhang''' (04/2013-11/2014)<br/>
+
 
Ph.D., Institute of Genetics and Developmental Biology, Chinese Academy of Sciences<br/>
+
'''Meghna Gopalan''' (06/2022-08/2022), '''Undergrad Summer Research Assistant'''
Then: Postdoc<br/>
+
 
Now: Postdoc, Xuemei Chen lab, UC Riverside
+
Email: mg4166 (at) barnard (dot) edu
 +
 
 +
*Barnard College
 +
 
 +
|
 +
 
 +
|
  
 
|-
 
|-
 
|style="width: 1px"|
 
|style="width: 1px"|
'''Jie Wu''' (01/2013-08/2013)<br/>
 
  
Then: Visiting Ph.D. student, Cold Spring Harbor Laboratory / Applied Maths and Statistics, Stony Brook University <br/>
+
'''Lydia Wu''' (10/2021-06/2022), '''Undergrad Research Assistant'''
Now: Bioinformatics Scientist, BioMicro Center, MIT
+
 
 +
 
 +
Email: lw2892 (at) columbia (dot) edu
 +
 
 +
*Columbia College
 +
 
 +
|
 +
 
 +
|
 +
 
 +
 
 +
 
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/lekha-yesantharao-9469399b/]]
 +
'''Lekha Yesantharao''' (09/2017-12/2019), '''Undergraduate Research Assistant'''
 +
 
 +
Undergraduate student, Department of Engineering, Columbia University<br/>
 +
Email: lvy2002 (at) columbia (dot) edu <br/>
 +
 
 +
*Simons Foundation Undergraduate Summer Research Program Award (2018)
 +
 
 +
|
 +
Medical School, Johns Hopkins School of Medicine
 +
 
 +
|
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/justin-wong-23155411b/]]
 +
'''Justin Wong''' (06/2017-05/2019), '''Undergraduate Research Assistant'''
 +
 
 +
Undergraduate student, Department of Computer Science, Columbia University<br/>
 +
Email: justin (dot) wong (at) columbia (dot) edu <br/>
 +
 
 +
*Simons Foundation Undergraduate Summer Research Program Award (2017)
 +
 
 +
|
 +
Graduate Student, UC Berkeley
 +
 
 +
|
 +
 
 +
 
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/18kbeyond/]]
 +
'''Yingzhi Qian''' (06/2016-06/2018), '''Computational Biologist'''
 +
 
 +
Email: yq2139 (at) columbia (dot) edu <br/>
 +
 
 +
*M.A., Statistics, Columbia University
 +
*B.Sc., Applied Mathematics, Fudan University
 +
 
 +
|
 +
Research Scientist, NYU Lagone Health
 +
 
 +
|
 +
Model Risk Management, Barclays
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
'''Helene Lovett''' (06/2017-08/2017), '''Undergraduate Research Assistant'''
 +
 
 +
Undergraduate student, Department of Neurobiology, Harvard University<br/>
 +
Email: helenelovett (at) college (dot) Harvard (dot) edu <br/>
 +
 
 +
*SURF/Amgen Fellowship (2017)
 +
|
 +
 
 +
|
 +
 
 +
 
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/ankeetashah/]]
 +
'''Ankeeta Shah''' (08/2015-05/2017), '''Volunteer'''
 +
 
 +
Undergraduate student, Barnard College<br/>
 +
Email: abs2218 (at) barnard (dot) edu
 +
 
 +
* SURF/Amgen Fellowship (2016)
 +
* Goldwater Scholarship (2016)
 +
 
 +
|
 +
Graduate Student, University of Chicago
 +
 
 +
|
 +
 
 +
Equity Research Associate, Piper Sandler
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
'''Jonah Lee''' (05/2015-01/2017), '''Volunteer'''
 +
 
 +
Undergraduate student, Columbia College<br/>
 +
Email: jl3910 (at) columbia (dot) edu
 +
 
 +
|
 +
 
 +
|
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
'''Andrew Arditi''' (Volunteer, 09/2016-12/2016)<br/>
 +
Columbia College<br/>
 +
Email: ava2123 (at) columbia (dot) edu
 +
 
 +
|
 +
 
 +
|
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
'''Jingxian You''' (Volunteer, 07/2016-09/2016)<br/>
 +
Fudan University<br/>
 +
Email: ykevingrox (at) gmail (dot) com
 +
 
 +
|
 +
 
 +
|
 +
|-
 +
 
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/jiayeli/]]
 +
'''Jiaye Li''' (05/2016-08/2016)<br/>
 +
 
 +
MA in Biotechnology, Columbia University
 +
 
 +
Volunteer
 +
 
 +
|
 +
 
 +
|
 +
Co-Founder, EleGo Education
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
[[File:LinkedIn.png|20px|link=http://www.linkedin.com/in/kevin-h-3b51b6125/]]
 +
'''Kevin Huynh''' (10/2015-7/2016)<br/>
 +
*BS, Biochemistry/Cell Biology, UCSD
 +
*MS, Biology, UCSD
 +
 
 +
Technician
 +
|
 +
 
 +
MD program, UCSF
 +
|
 +
 
 +
Resident Physician, UCSF
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
'''Joy Pai''' ( 09/2013-05/2016)<br/>
 +
Undergraduate student, Departments of Biological Sciences and Computer Science, Columbia University<br/>
 +
* Harvard/MIT HST Summer Institute Fellowship (2015)
 +
* SURF/Amgen Fellowship (2014)
 +
 
 +
Undergraduate Research Assistant
 +
|
 +
Bioinformatics specialist, Michel Russenzweig lab, Rockefeller University
 +
|
 +
Graduate Student, Stanford University
 +
 
 +
|-
 +
|style="width: 1px"|
 +
 
 +
'''Kernyu Park''' (07/2015-10/2015)<br/>
 +
Departments of Biological Sciences and Computer Science, Columbia University
 +
 
 +
Undergraduate Research Assistant
 +
|
 +
 
 +
|
 +
 
  
 
|}
 
|}

Latest revision as of 14:47, 17 October 2024

Zhang lab photo, 2024 @ Columbia University Irving Medical Center

Zhang lab photo, 2024 @ Columbia University Irving Medical Center


PI

Chaolin2022.jpg

Chaolin Zhang Twitter.jpg LinkedIn.png

Associate Professor, Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, Motor Neuron Center
Email: cz2294 (at) columbia (dot) edu

Curriculum Vitae

Personal page (old!)

Chaolin is currently an Associate Professor with joint appointments in Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, and Motor Neuron Center at Columbia University Irving Medical Center. Before he joined Columbia, he performed PhD studies at Cold Spring Harbor Laboratory in computational biology and then Postdoc work on computational and molecular biology at Rockefeller University. Before that he obtained bachelor's degree studying Automation at Tsinghua University (Beijing). As an engineer-converted biologist, he has a deep interest in understanding gene regulatory logics. From the beginning of his academic endeavor, he decided to tackle the RNA code, i.e., how specific protein-RNA interactions determine the gene output in health and disease conditions, which remains the focus of the lab. Chaolin is a winner of Pathway to Independence Award (K99/R00, 2011) and Maximizing Investigators' Research Award (MIRA/R35, 2022) from NIH, and Scientific Innovations Award from the Brain Research Foundation (2023).



Current Lab Members


ChamariAbercrombie.jpg

LinkedIn.png

Chamari Abercrombie (07/2024-), Postbac

Email: ca3176 (at) columbia (dot) edu

  • BA, Neuroscience-Biology, College of Wooster

Chamari received her BA in Neuroscience-Biology from The College of Wooster in Ohio. During her last year of undergrad, she completed her Independent Study by analyzing epilepsy in Drosophila melanogaster. Chamari’s goal is to pursue an MD/PhD as a neurosurgeon to contribute to research that aligns with her goals of providing adequate patient care and development of effective but safe medication. Originally from Atlanta, Georgia, Chamari is excited to explore the city. In her free time, she loves to work out and try new restaurants.


Shahalam.jpg

LinkedIn.png

Shah Alam (06/2023-), Postdoc

Email: sa4354 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Molecular Medicine, University of Bonn, Germany

Shah joined Zhang's lab in June 2023 as a postdoctoral research scientist. Prior to joining Columbia, he gained experience working as a postdoc at the LIMES Institute, University of Bonn, Germany, for over a year. He also completed his PhD at the same institute. During his PhD, he unraveled the signaling of sphingosine-1-phosphate (S1P) in primary neurons, microglia, and astrocytes of a neurodegenerative disease mouse model called neural-cell specific S1P-lyase (SGPL1) deficient mice. He earned his master's degree in molecular biotechnology from the University of Bonn and his bachelor's degree in biotechnology from VIT University, India. Shah's current research plans involve delving into the regulatory mechanisms and lineage-specific alternatively splicing events and their functional impacts on brain development and developmental disorders. Moreover, he is also interested in developing experimental systems that will strategically map and compare RBP binding sites and RBP-dependent splicing regulation in neurons. Beyond his academic pursuits, he is particularly passionate about cricket, running, and hiking.


Shane chu.jpg

LinkedIn.png

Shane Chu (01/2024-), Postdoc

Email: sc5502 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Department of Computer Science, Washington University at Saint Louis

Personal page

Shane Chu earned his PhD in computer science from Washington University in St. Louis, working with Gary Stormo. His PhD work focused on developing interpretable representation learning methods for addressing challenges in protein-DNA/RNA interactions. Outside of his academic pursuits, he finds relaxation and enjoyment in playing tennis and visiting the Peridance Center in NYC.



Wangyang.jpg

Wangyang Dai (10/2023-), Master Student

Email: wd2383 (at) columbia (dot) edu

  • Master student, Biotechnology, Columbia University
  • BS, Fudan University, Shanghai, China (2023)

Wangyang obtained her Bachelor's degree in Life Sciences from Fudan University in 2023. During her time as an undergraduate student, she conducted research on proline metabolism and its effects on ATF4 regulation. Later, she developed an interest in the RNA world (cool!), specifically focusing on alternative splicing and its correlation with neuron cell properties within and across cell types. Now in the Zhang lab, she is involved in a project about analysis of CLIP data using crosslink-induced mutation sites (CIMS) and aims to utilize it as a signature to better understand RBP binding specificity. Besides academics, she enjoys exploring good food, visiting museums, and building her own coffee map here in New York.




Jassicae2022.jpg

LinkedIn.png

Jessica Estrada (11/2022-), Technician

Email: je2673 (at) cumc (dot) columbia (dot) edu

  • BA, Chemistry, Stony Brook University

Jessica received her B.A from Stony Brook University in Chemistry and is a Technician in the Zhang Lab. She assists on various projects in the lab while developing a research focus, and plans on pursing a PhD in the biomedical sciences. In her free time, she likes to go on hikes and cook for friends and family.



Brian2022v2.jpg

LinkedIn.png

Brian Joseph (11/2021-), Postdoc (joint with Hynek Witchterle lab)

Email: bj2468 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Gerstner Sloan Kettering Graduate School of Biomedical Sciences
  • New York Stem Cell Foundation Research Institute (NYSCF) Druckenmiller Fellows (2023)

Brian joined the Zhang and Wichterle labs as a postdoctoral fellow in November 2021 after a brief research experience in Kevin Eggan’s motor neuron lab at Harvard. He completed his PhD with Eric Lai at the Sloan Kettering Institute in NYC focusing on the biology of cotranscriptional RNA processing mechanisms. He plans to explore RNA metabolism in neurons and hopes to identify novel vulnerabilities that can be the basis for therapeutic intervention. Brian is currently an ALS scholar in therapeutics.

A native Pakistani, Brian is obsessed with cricket and biryani. He is also an avid runner who still believes the PRs are yet to come.



Dan2022.jpg

LinkedIn.png

Daniel Moakley (06/2018-), Graduate Student

Email: dfm2129 (at) cumc (dot) columbia (dot) edu

  • Ph.D. student, Integrative Program, Columbia University


Before coming to Columbia, Dan earned Bachelor’s and Master’s degrees from Wesleyan University, where he studied the maturation of ESC-derived interneurons in Laura Grabel’s laboratory. Then, he worked with Brian Wainger at Massachusetts General Hospital, where he focused on the electrophysiology of ESC-derived motor neurons. Dan is interested in molecular underpinnings of the immense cell type diversity in the brain. His work leverages both computational and experimental techniques to examine neuron type-specific alternative RNA splicing regulation. He uses the reanalysis of large, publicly available data sets to identify potential regulators of splicing differences across neuron types. These hypotheses are then tested in embryonic stem cell (ESC)-derived neurons.




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Paola Rinchetti (05/2022-), Postdoc

Email: pr2485 (at) cumc (dot) columbia (dot) edu

  • Ph.D., University of Milan

Paola's research career started in 2014 in Prof. Stefania Corti's lab at University of Milan. During her studies in Italy, she maximized her knowledge in the field of cellular biology and in particular in the use of induced pluripotent stem cells (iPSCs) and 2D models to study neurodegenerative diseases such as SMA and ALS and the development of potential treatments. During her PhD, she mainly focused on the generation of new 3D models to investigate the pathological mechanism underlying SMA and ALS. During this time, she was also involved in exchange programs with the laboratory of Prof. Prezdborsky and Prof. Lotti at Columbia University where she was able to deepen her knowledge in the field of in vivo models. In the Zhang lab, she is working on RNA-based medicine for neurodevelopmental disorders.


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Lea Radomsky (09/2024-), Technician

Email: lr3280 (at) columbia (dot) edu

  • Certified Professional Training as Biology Lab Technician, Technical University of Munich, Germany

Lea completed her vocational training in Germany at the Technical University of Munich from 2018 to 2021. Between 2018 and 2024, she worked with Prof. Angelika Schnieke and Prof. Benjamin Schusser, focusing on advanced molecular and cell culture techniques. In September 2024, she joined the Zhang lab, where she supports postdoctoral researchers with molecular experiments and cell culture work. Outside the lab, Lea enjoys Pilates and exploring New York City.


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Ruchika (07/2023-), Postdoc

Email: fr2563 (at) columbia (dot) edu

  • PhD, School of Material Science, Japan Advanced Institute of Science and Technology, Japan

Ruchika completed her doctoral degree in molecular biology from Japan Advanced Institute of Science and Technology (JAIST) in Japan in 2022. During PhD, she worked on the identification and characterization of U-to-C RNA editing events in plants and used a plant-derived pentatricopeptide repeat (PPR) proteins to develop an artificial deamination system for C-to-U RNA editing in mammalian cells, and received an Excellent student award for her work. Thereafter, she joined Kyushu University in Fukuoka, Japan, as an assistant professor and she worked on designer PPR proteins to target long non-coding RNAs, especially related to neurodegenerative diseases and cancer. At the next step, Ruchika is excited for multiple projects related to programmable RNA targeting using different approaches at Columbia.



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Tianxin (Cynthia) Wang (09/2024-), Graduate Student (in Rotation)

Email: tw3056 (at) columbia (dot) edu

  • B.S., Biological Sciences, University of Chicago

Cynthia is a first-year PhD student in the Systems Biology Department. Before coming to Columbia, she earned her Bachelor’s from the University of Chicago. During her studies, she conducted both experimental and computational research and developed a passion for the RNA world. In Prof. Tao Pan’s lab, she facilitated the development and optimization of an engineered missense-correcting tRNA as potential therapeutics for correcting pathogenic mutations. In Prof. Matthias Steinruecken's lab, she statistically evaluated how including the genetically linked locus affected the time-series inference of natural selection at its surrounding loci. Now, she has joined the Zhang lab as a rotation student, where she is excited to work on designing tools to target neurodegenerative disease-related RNAs. Outside of lab, she enjoys doing yoga, working out, exploring good food, and traveling to experience diverse cultures.


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Xiaojian Wang (06/2016-), Lab manager

Email: xw2006 (at) columbia (dot) edu

  • MS, Molecular, Cellular and Developmental biology, the Ohio State University
  • BM, Basic Medical Sciences, Beijing Medical University, Beijing, China

Before coming to work at Columbia, Xiaojian earned her Bachelor’s and Master’s degrees from Beijing Medical University and the Ohio State University, respectively. At CUIMC, she worked as supporting staff and lab manager in several labs. She joined the Zhang lab in 2016, and has been providing support on both molecular biology experiments and mouse work, as well as daily lab operations. In her free time, Xiaojian enjoys cooking, watching baseball games, and spending time with her family.


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Ye Wang (02/2024-), Postdoc

Email: yw4291 (at) columbia (dot) edu

  • PhD, Tsinghua National Laboratory for Information Science and Technology, Department of Automation, Tsinghua University, Beijing, China.

Prior to joining Zhang lab, Ye obtained her PhD training on computational and synthetic biology in Tsinghua university. During her PhD, she proposed an AI-based generative framework for the de novo design of promoter elements in Escherichia coli, which showed a high success rate based on experimental validation in vivo. For her postdoc research, she plans to focus on inverse design of synthetic exons/introns to understand splicing regulation and their function in brain and developmental disorders, with an ultimate goal to facilitate the development of RNA-based precision genetic medicine. Outside the lab, Ye is passionate about yoga, running, and cooking.


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Tim Yeh (09/2022-), Postdoc


Email: yy2722 (at) cumc (dot) columbia (dot) edu

  • PhD, Department of Biology, Zukerman Mind Brain Behavior Institute, Columbia University

Tim received his Ph.D. in Biological Sciences from Columbia University (2022). Throughout his scientific career, he has been interested in understanding how the brain works and developing treatment. His graduate research focused on auditory processing in the brain and sensorimotor interaction. As a postdoc in the Zhang lab, Tim hopes to investigate the roles of RNA splicing in normal brain functions and neurological diseases using novel research methods such as gene editing tools and sequencing technologies. When he is not doing science, he likes to play tennis and ping pong. He is also a foodie who enjoys eating pizza!

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Tianji Yu (07/2024-), Graduate Student


Email: ty2514 (at) cumc (dot) columbia (dot) edu

  • BA, Quantitative Biology, UNC Chapel Hill

Tianji is a first-year Ph.D. student in the Systems Biology Department. Before he came to Columbia, he earned a Bachelor's degree from UNC Chapel Hill. At UNC, his research focused on cell cycle regulation in endothelial cells and AU-rich elements RNA binding proteins. During his undergraduate research, he practiced both experimental and computational techniques. Now he is excited to conduct new research here at Columbia University. In Zhang's lab, he is working on RNA base editing for his rotation project. Besides research, he likes soccer and food. He is also fascinated with karting race.


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Matthew Yuan (06/2023-), Visiting High School Student (remote)

Matthew currently attends Lynbrook High School in San Jose, California as a rising Sophomore, and is passionate about Math and Science. Matthew is a two-time AIME qualifier, and has years of experience in Science Olympiad and Science Bowl. His favorite research area is Marine Biology. In his spare time, Matthew enjoys reading and writing, playing basketball as well as playing video games (Geometry Dash and Crossy Road are his favorites).



Alumni

Name/Position in the Lab

Position When Exiting

Current Position



LinkedIn.png Suvrajit Maji (07/2022-06/2024), Postdoc

Email:sm4073 (at) cumc (dot) columbia (dot) edu

  • Ph.D.,Carnegie Mellon University

Personal page


Senior Research Scientist, NYU Langone Health


LinkedIn.png Yocelyn Recinos (06/2018-01/2024), Graduate Student

Email: yr2330 (at) cumc (dot) columbia (dot) edu

  • Ph.D. student, Integrative Program, Columbia University
  • NSF GRFP awardee (2019)
  • Dean's Award for Excellence in Research (2024)
Scientific Analyst, Morrison Foerster


LinkedIn.png Georgia Dermentzaki (09/2021-11/2023), Postdoc

Email: gn2267 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Neuroscience, University of Athens; Biomedical Research Foundation of the Academy of Athens, Athens, Greece

Senior Scientist, Sanofi


LinkedIn.png Melissa Campbell (09/2019-11/2022), Postdoc

Email: mmc2259 (at) cumc (dot) columbia (dot) edu

  • M.D./Ph.D., Department of Genetics, NYU
  • NIH K99 awardee (2021)

Assistant Professor, UCSD


LinkedIn.png Huijuan Feng (8/2016-12/2021), Postdoc

Email: hf2304 (at) columbia (dot) edu

  • Ph.D., MOE Key Laboratory of Bioinformatics, Bioinformatics Division, TNLIST & Department of Automation, Tsinghua University
  • Visiting Ph.D. student (1/2015-1/2016)

Personal page

Associate Professor, Fudan University

LinkedIn.png Suying Bao (06/2017-06/2021), Postdoc

Email: sb4045 (at) columbia (dot) edu

  • Ph.D., School of Biomedical Sciences, The University of Hong Kong

Bioinformatics Manager, Regeneron

Seinior Manager Computational Genomics, Regeneron

LinkedIn.png Dmytro Ustianenko (01/2015-05/2021), Postdoc

Email: du2145 (at) columbia (dot) edu

  • Ph.D., Biomolecular Chemistry, Masaryk University, Central European Institute of Technology, Brno, Czech Republic

Blavatnik Fellow in Life Science Entrepreneurship, Yale University

Associate, Flagship Pioneering

LinkedIn.png Brittany Phillips (05/2018-05/2019), Postdoc

Email: bp2563 (at) cumc (dot) columbia (dot) edu

  • Ph.D., Genetics and Molecular Biology, Emory University

Medical Writer, Chrysalis Medical Communications

Medical Writing Senior Manager, Amgen

LinkedIn.png Sebastien Weyn (08/2013-02/2018), Graduate Student

Ph.D. student, Integrative Program, Columbia University
Email: smw2185 (at) columbia (dot) edu

  • Titus M Coan Award for Excellence in Research (2018)

Bioinformatics Scientist, Stoke Therapeutics.

Principal Scientist, Bioinformatics, Fosun Pharma USA Inc.

LinkedIn.png Martin Jacko (08/2013-07/2017), Graduate Student

Ph.D. student (joint with Wichterle lab), Department of Pathobiology & Molecular Medicine, Columbia University
Email: mj2577 (at) columbia (dot) edu

Postdoc, Alice Ting Lab, Stanford University

CEO, Aperture Therapeutics

LinkedIn.png Qinghong Yan (02/2013-02/2015), Postdoc
Ph.D., Department of Neurobiology & Behavior, Stony Brook University


Scientist, Amgen

CSO, Leverna Therapeutics

Yong Zhang (04/2013-11/2014), Postdoc
Ph.D., Institute of Genetics and Developmental Biology, Chinese Academy of Sciences


Postdoc, Xuemei Chen lab, UC Riverside

Research Scientist, USDA

LinkedIn.png Jie Wu (01/2013-08/2013)

Visiting Ph.D. student, Cold Spring Harbor Laboratory / Applied Maths and Statistics, Stony Brook University

Bioinformatics Scientist, BioMicro Center, MIT

Associate Director, Bioinformatics at Accent Therapeutics, Inc.



Qiyang Wu (01/2013-), Master Student

Email:qw2388 (at) columbia (dot) edu

  • Master of Science Program in Biomedical Engineering, Columbia University
  • BE, The Chinese University of Hong Kong, Shenzhen, China (2022)



LinkedIn.png Fahad Paryani (09/2023-), Rotation Student

Email: fp2409 (at) cumc (dot) columbia (dot) edu

  • Ph.D. student, Integrated Program, Columbia University



LinkedIn.png Albertine Neal (09/2023-), Rotation Student

Email: amn2201 (at) cumc (dot) columbia (dot) edu

  • Ph.D. student, Integrated Program, Columbia University

LinkedIn.png Tianji Yu (09/2023-), Rotation Student


Email: ty2514 (at) cumc (dot) columbia (dot) edu

  • BA, Quantitative Biology, UNC Chapel Hill


Madeline (Maddie) Scanlon (06/2023-09/2023), Visiting High School Student


  • High school studnet, King School, Stamford, CT

Vivian Coraci (07/2023-09/2023), Visiting High School Student


  • High school student, Horace Mann School in the Bronx.

Yuchen Xu (02/2022-05/2023), Master Student


Email: yx2709 (at) cumc (dot) columbia (dot) edu

  • Public Health in Biostatistics, Columbia University

Research Technician, Abbas Rizvi Lab, University of Wisconsin-Medison


Lily Wang (07/2020-09/2020), Undergraduate Research Assistant

Undergraduate student, Mathematics/Statistics, Columbia University
Email: hw2744 (at) columbia (dot) edu

  • Amgen Summer Research Program Award (2020)

Meghna Gopalan (06/2022-08/2022), Undergrad Summer Research Assistant

Email: mg4166 (at) barnard (dot) edu

  • Barnard College

Lydia Wu (10/2021-06/2022), Undergrad Research Assistant


Email: lw2892 (at) columbia (dot) edu

  • Columbia College



LinkedIn.png Lekha Yesantharao (09/2017-12/2019), Undergraduate Research Assistant

Undergraduate student, Department of Engineering, Columbia University
Email: lvy2002 (at) columbia (dot) edu

  • Simons Foundation Undergraduate Summer Research Program Award (2018)

Medical School, Johns Hopkins School of Medicine

LinkedIn.png Justin Wong (06/2017-05/2019), Undergraduate Research Assistant

Undergraduate student, Department of Computer Science, Columbia University
Email: justin (dot) wong (at) columbia (dot) edu

  • Simons Foundation Undergraduate Summer Research Program Award (2017)

Graduate Student, UC Berkeley


LinkedIn.png Yingzhi Qian (06/2016-06/2018), Computational Biologist

Email: yq2139 (at) columbia (dot) edu

  • M.A., Statistics, Columbia University
  • B.Sc., Applied Mathematics, Fudan University

Research Scientist, NYU Lagone Health

Model Risk Management, Barclays

Helene Lovett (06/2017-08/2017), Undergraduate Research Assistant

Undergraduate student, Department of Neurobiology, Harvard University
Email: helenelovett (at) college (dot) Harvard (dot) edu

  • SURF/Amgen Fellowship (2017)


LinkedIn.png Ankeeta Shah (08/2015-05/2017), Volunteer

Undergraduate student, Barnard College
Email: abs2218 (at) barnard (dot) edu

  • SURF/Amgen Fellowship (2016)
  • Goldwater Scholarship (2016)

Graduate Student, University of Chicago

Equity Research Associate, Piper Sandler

Jonah Lee (05/2015-01/2017), Volunteer

Undergraduate student, Columbia College
Email: jl3910 (at) columbia (dot) edu

Andrew Arditi (Volunteer, 09/2016-12/2016)
Columbia College
Email: ava2123 (at) columbia (dot) edu

Jingxian You (Volunteer, 07/2016-09/2016)
Fudan University
Email: ykevingrox (at) gmail (dot) com

LinkedIn.png Jiaye Li (05/2016-08/2016)

MA in Biotechnology, Columbia University

Volunteer

Co-Founder, EleGo Education

LinkedIn.png Kevin Huynh (10/2015-7/2016)

  • BS, Biochemistry/Cell Biology, UCSD
  • MS, Biology, UCSD

Technician

MD program, UCSF

Resident Physician, UCSF

Joy Pai ( 09/2013-05/2016)
Undergraduate student, Departments of Biological Sciences and Computer Science, Columbia University

  • Harvard/MIT HST Summer Institute Fellowship (2015)
  • SURF/Amgen Fellowship (2014)

Undergraduate Research Assistant

Bioinformatics specialist, Michel Russenzweig lab, Rockefeller University

Graduate Student, Stanford University

Kernyu Park (07/2015-10/2015)
Departments of Biological Sciences and Computer Science, Columbia University

Undergraduate Research Assistant